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Benoquin - Clinical PharmacologyBenoquin Cream 20% is a depigmenting agent whose mechanism of action is not fully understood.The topical application of monobenzone in animals, increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation. This effect is erratic and may take one to four months to occur while existing melanin is lost with normal stratum corneum sloughing. Hyperpigmented skin appears to fade more rapidly than does normal skin, and exposure to sunlight reduces the depigmenting effect of the drug. After depigmentation with topical monobenzone, the histology of the skin is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes.

What is the use of Benoquin monobenzone cream?

BRAND NAME(S): Benoquin. USES: Monobenzone is used to treat the uneven appearance of the skin due to a loss of skin color (vitiligo). It works by permanently removing color from normal skin located around the skin with vitiligo.

Can I use Benoquin for skin whitening?

Benoquin Cream 20% contains a potent depigmenting agent and is not a cosmetic skin bleach. Use of Benoquin Cream 20% is contraindicated in any conditions other than disseminated vitiligo. Use only for final depigmentation in extensive vitiligo.

Is Benoquin cream permanent?

Benoquin is a topical prescription drug approved by the U.S. Food and Drug Administration (FDA) for removing pigment in people with vitiligo that covers more than 50 percent of their body. 1,2 The skin-bleaching effects of Benoquin are permanent and irreversible.

How does monobenzone work?

It achieves its effects by inducing the necrotic death of melanocytes. Topical all-trans-retinoic acid (RA), a vitamin A derivative, causes mild depigmentation and, when combined with MBEH, has synergistic effects, yielding depigmentation quickly.

Benoquin Monobenzone Cream Price In Pakistan Is 6,999/-PKR